carpal tunnel syndrome

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	190
interventional	158
Observational	30
Registry	2

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Procedure	38
Device	26
Other	23
Drug	21
Drug|Other	6
Drug|placebo	6
Other|Procedure	6
Device|Drug	5
Device|Procedure	5
Behavioral	3
Drug|Procedure	3
Other|placebo	3
Diagnostic Test	2
placebo|Procedure	2
Biological|Device	1
Combination Product|Device	1
Device|Drug|placebo|Procedure	1
Device|Drug|Procedure	1
Device|Other	1
Device|placebo	1
Dietary Supplement|Procedure	1
Drug|Other|placebo	1
Drug|Other|Procedure	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	42
Taiwan	23
NA	16
Spain	14
Canada	11
Egypt	9
Turkey	5
Brazil	4
Denmark	3
Italy	3
United Kingdom	3
Belgium	2
China	2
Israel	2
Mexico	2
Sweden	2
Austria	1
Chile	1
Finland	1
France	1
Hong Kong	1
Jordan	1
Korea, Republic of	1
Netherlands	1
New Zealand	1
Norway	1
Poland	1
Syrian Arab Republic	1
Thailand	1
United States|Canada	1
Venezuela	1

Sites per Study

Site_count	Study_Count
1	143
2	8
3	4
6	1
7	2

Phase

Phase	Study_Count
N/A	112
Phase 4	18
Phase 2	11
Phase 1/Phase 2	5
Phase 3	4
Phase 1	3
Phase 2/Phase 3	3
Early Phase 1	2

Number of Arms

Number_of_Arms	Count_of_Studies
1	17
2	104
3	25
4	7
6	1
NA	4

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	60	2.000	80.0000	10	10.00000	20	39.00	30.0000
1st Qu.	70	40.000	85.0000	40	22.00000	55	39.75	52.5000
Median	80	60.000	90.0000	60	40.00000	90	62.00	68.0000
Mean	80	79.125	123.3333	46	73.63636	74	78.25	129.2222
3rd Qu.	90	100.000	145.0000	60	119.00000	101	100.50	107.2500
Max.	100	488.000	200.0000	60	240.00000	112	150.00	650.0000

Trial Group Type

group_type	Group_Count
Experimental	134
Active Comparator	118
Placebo Comparator	34
No Intervention	19
Other	17
Sham Comparator	12
NA	4

Intervention Model

intervention_model	Study_Count
Parallel Assignment	127
Single Group Assignment	19
Crossover Assignment	7
Factorial Assignment	4
NA	1

Primary Purpose

primary_purpose	Study_Count
Treatment	135
Diagnostic	6
Supportive Care	6
Other	4
Prevention	4
Health Services Research	3

Observational Studies

Studies by Country

Country	Study_Count
United States	14
NA	5
Sweden	2
Switzerland	2
China	1
Egypt	1
Germany	1
Japan	1
Poland	1
Taiwan	1
United Kingdom	1

Sites per Study

Site_count	Study_Count
1	27
2	2
3	1

Enrollment Metrics

Measure	Observational
Min	4.0000
1st Qu	51.2500
Median	98.0000
Mean	333.4667
3rd Qu	172.0000
Max	6048.0000

Observation Model

observational_model	Study_Count
Cohort	11
Case-Control	8
Case Control	5
Case-Only	3
Natural History	1
Other	1
NA	1

Time Perspective

time_perspective	Study_Count
Prospective	19
Retrospective	6
Cross-Sectional	4
Longitudinal, Prospective	1

Registries

Studies by Country

Country	Study_Count
NA	1
United States	1

Sites per Study

Site_count	Study_Count
1	2

Enrollment Metrics

Measure	Registries
Min	33.00
1st Qu	25024.75
Median	50016.50
Mean	50016.50
3rd Qu	75008.25
Max	100000.00

Registry Model

observational_model	Study_Count
Case-Control	1
Ecologic or Community	1

Time Perspective

time_perspective	Study_Count
Other	1
Prospective	1

Follow-up

target_duration	Study_Count
2 Months	1
3 Years	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03111186	Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery	https://ClinicalTrials.gov/show/NCT03111186	Completed	University of Southern California	2019-05-01
NCT03407820	Different Sutures in Hand Surgery	https://ClinicalTrials.gov/show/NCT03407820	Active, not recruiting	University of Texas at Austin	2020-05-30
NCT03381521	The Volume Effect of Nerve Hydrodissection for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03381521	Recruiting	Tri-Service General Hospital	2021-12-31
NCT03360344	Non-surgical Intervention for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03360344	Completed	Loma Linda University	2018-10-23
NCT03294733	The Relationship Between Age and Carpal Tunnel Size	https://ClinicalTrials.gov/show/NCT03294733	Completed	Mayo Clinic	2020-02-01
NCT03243227	Effectiveness of Neurodynamic Techniques for the Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03243227	Completed	University of Jordan	2019-07-01
NCT03205683	Intraneural Facilitation as a Treatment for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03205683	Completed	Loma Linda University	2019-02-22
NCT03184688	Platelet Rich Plasma for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03184688	Completed	Tri-Service General Hospital	2019-10-30
NCT03180125	Hyaluronic Acid Hydro-dissection Use in Idiopathic Carpal Tunnel Syndrome Guided by Ultrasonic Study	https://ClinicalTrials.gov/show/NCT03180125	Completed	Assiut University	2017-10-01
NCT03177915	Median Nerve Hydro-dissection Using Single Injection of Hyalase as a Novel Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03177915	Completed	Assiut University	2016-12-31
NCT03169218	Effects of Mirror Therapy on Pain and Function on Bilateral Carpal Tunnel Syndrom	https://ClinicalTrials.gov/show/NCT03169218	Completed	Hospital de Manises	2017-01-31
NCT03072290	Corticosteroid Injection in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03072290	Completed	Taipei Veterans General Hospital, Taiwan	2018-11-28
NCT03036657	Local Effects of Acupuncture and Nerve Conduction Studies	https://ClinicalTrials.gov/show/NCT03036657	Recruiting	Oregon Health and Science University	2020-05-31
NCT03031054	The Effect of Hyaluronic Acid for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03031054	Completed	Tri-Service General Hospital	2019-10-28
NCT03031041	Comparison of Difference Hydrodissection for CTS	https://ClinicalTrials.gov/show/NCT03031041	Completed	Tri-Service General Hospital	2019-08-30
NCT02991001	The Effect of Hydrodissection for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02991001	Completed	Tri-Service General Hospital	2018-04-15
NCT02990962	The Effect of Perineural Injection Therapy Versus Steroid in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02990962	Completed	Tri-Service General Hospital	2018-04-01
NCT02986828	Platelet Rich Plasma and Hydrodissection for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02986828	Completed	Tri-Service General Hospital	2019-10-30
NCT02986347	Surgical Treatment of Carpal Tunnel Syndrome: Local Anesthesia With Epinephrine x Intravenous Regional Anesthesia.	https://ClinicalTrials.gov/show/NCT02986347	Completed	Hospital Alvorada	2020-01-01
NCT04453462	Efficacy of Local Direct Median Nerve Block	https://ClinicalTrials.gov/show/NCT04453462	Recruiting	Thammasat University	2020-08-01
NCT02885701	Splinting After Mini-Open Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT02885701	Completed	OrthoIllinois	2015-01-31
NCT02809261	The Effect of Perineural Injection Therapy in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02809261	Completed	Tri-Service General Hospital	2017-03-30
NCT02800200	The Effect of Combined PRP and ESWT for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02800200	Completed	Tri-Service General Hospital	2017-09-15
NCT02800187	The Dose Effect of Extracorporeal Shock Wave Therapy in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02800187	Completed	Tri-Service General Hospital	2017-10-31
NCT02766114	Carpal Tunnel Release Through Mini Transverse Approach	https://ClinicalTrials.gov/show/NCT02766114	Completed	Issa, Abdulhamid Sayed, M.D.	2016-03-31
NCT02745652	Carpel Tunnel Syndrome and Physical Therapy Modalities	https://ClinicalTrials.gov/show/NCT02745652	Completed	Cairo University	2015-01-31
NCT02708693	Efficacy of Combined Ultrasound Guided Steroid Injection and Splinting in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02708693	Completed	Taipei Veterans General Hospital, Taiwan	2014-04-30
NCT02706418	Clinical Massage Therapy as a Treatment for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02706418	Completed	Jing Advanced Massage Training	2017-08-31
NCT02698085	Diacutaneous Fibrolysis on Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02698085	Completed	Universidad de Zaragoza	2016-09-01
NCT02696161	Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02696161	Completed	Tri-Service General Hospital	2017-07-31
NCT02652390	Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02652390	Completed	Region Skane	2016-10-31
NCT02609113	Static Magnetic Therapy for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02609113	Completed	Wake Forest University Health Sciences	2016-10-21
NCT02575729	Sonography-guided Steroid Injection for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02575729	Completed	Chang Gung Memorial Hospital	2014-07-31
NCT02038452	Injection Versus Splinting in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02038452	Completed	Keele University	2016-12-31
NCT03394131	ُEfficacy of Insulin Versus Hyalase Hydro-dissection of Median Nerve in Rheumatoid Arthritis Patients	https://ClinicalTrials.gov/show/NCT03394131	Recruiting	Assiut University	2018-05-01
NCT02553811	Diagnosis of Carpal Tunnel Syndrome: Effectiveness of Diagnostic Tests. Clinical Trial of Accuracy	https://ClinicalTrials.gov/show/NCT02553811	Completed	Federal University of São Paulo	2016-06-30
NCT02539186	The Effect of Platelet Rich Plasma for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02539186	Completed	Tri-Service General Hospital	2017-09-30
NCT02534493	Safety and Efficacy of a Novel Carpal Tunnel Tissue Manipulation Device in Treating Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02534493	Completed	Pressure Profile Systems, Inc.	2016-09-30
NCT02514317	Percutaneous Treatment of Carpal Tunnel Syndrome With Scan	https://ClinicalTrials.gov/show/NCT02514317	Completed	University Hospital, Caen	2013-03-31
NCT02500355	Carpal Tunnel Release Via Two Small Incisions Comparing With Via Standard Incision And Under Endoscope	https://ClinicalTrials.gov/show/NCT02500355	Completed	The Second Hospital of Qinhuangdao	2013-02-28
NCT02495298	Fascial Manipulation on the Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02495298	Completed	University of Sao Paulo	2013-12-31
NCT02382328	Alpha Lipoic Acid on Clinical and Electrophysiological Recovery in Carpal Tunnel Syndrome Undergoing Surgical Release	https://ClinicalTrials.gov/show/NCT02382328	Completed	Hospital Civil de Guadalajara	2016-06-30
NCT02315573	Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery	https://ClinicalTrials.gov/show/NCT02315573	Completed	St. Mary’s Research Center, Canada	2019-04-30
NCT02313675	Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries	https://ClinicalTrials.gov/show/NCT02313675	Completed	University of Pittsburgh	2017-05-01
NCT02278289	Comparative Effectiveness of Ultrasound and Paraffin Therapy in Patients With Carpal Tunnel Syndrome: A Randomized Trial	https://ClinicalTrials.gov/show/NCT02278289	Completed	Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation	2011-12-31
NCT02233660	The Role of the Cervical Spine in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02233660	Completed	Universidad Rey Juan Carlos	2016-03-31
NCT02219919	Nociceptive Gain Processing After Physical Therapy in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02219919	Completed	Universidad Rey Juan Carlos	2016-05-31
NCT02219555	DUCATS Trial: Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02219555	Recruiting	Mayo Clinic	2021-01-31
NCT02218229	The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02218229	Completed	Tri-Service General Hospital	2017-05-31
NCT02217293	Efficacy of Pulsed Radiofrequency of the Median Nerve Under Ultrasound Guidance in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02217293	Completed	Tri-Service General Hospital	2013-09-30
NCT02141035	Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02141035	Completed	University of Alberta	2017-06-30
NCT02140632	Efficacy Study of Local Steroid Injection and Wrist Splinting for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02140632	Completed	Kwong Wah Hospital	2015-12-31
NCT02101294	Study Protocol for CTS and Keyboard Controlled Randomized Trial	https://ClinicalTrials.gov/show/NCT02101294	Completed	Finger Relief	2008-07-31
NCT02071238	Factors Affecting Risk Recall in Open Carpal Tunnel Release Surgery	https://ClinicalTrials.gov/show/NCT02071238	Completed	Nova Scotia Health Authority	2015-10-31
NCT02070302	BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02070302	Completed	Arizona Arthritis & Rheumatology Research, PLLC.	2016-02-29
NCT01310218	Length of Post Operative Dressing After Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT01310218	Completed	UConn Health	2010-10-31
NCT02054247	Continuous And Pulsed Ultrasound Treatments On Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02054247	Completed	Eskisehir Osmangazi University	2013-06-30
NCT01993290	USG Brachial Plexus Block for Upper Extremity Surgery	https://ClinicalTrials.gov/show/NCT01993290	Completed	Bispebjerg Hospital	2014-10-31
NCT01974609	Narcotic vs. Non-narcotic Pain Study Protocol	https://ClinicalTrials.gov/show/NCT01974609	Active, not recruiting	Horizon Health Network	2020-06-30
NCT01972165	Comparison of Subjective Outcomes and Changes of Ultrasonographic Morphology of Median Nerves of Mini-open and Endoscopic Carpal Tunnel Release in Patients With Idiopathic Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT01972165	Completed	Yonsei University	2013-07-31
NCT01949493	Non-surgical Treatment of Carpal Tunnel Syndrome by Means of Mechanical Traction	https://ClinicalTrials.gov/show/NCT01949493	Completed	University of Tilburg	2016-06-30
NCT01895621	Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial.	https://ClinicalTrials.gov/show/NCT01895621	Completed	Istituto Ortopedico Rizzoli	2014-12-31
NCT01887145	Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT01887145	Completed	Region Skane	2014-11-30
NCT01789645	Physical Therapy in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT01789645	Completed	Universidad Rey Juan Carlos	2014-01-25
NCT01751347	Bupivacaine Versus Lidocaine Local Anesthesia	https://ClinicalTrials.gov/show/NCT01751347	Completed	University of British Columbia	2015-12-31
NCT01716767	Acute Effect of Topical Menthol on Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT01716767	Completed	National Research Centre for the Working Environment, Denmark	2013-01-31
NCT01632215	Preoperative Gabapentine for Carpal Tunnel	https://ClinicalTrials.gov/show/NCT01632215	Completed	Federal University of São Paulo	2011-08-31
NCT01590745	Ultrasound Therapy for Carpal Tunnel Syndrome (CTS)	https://ClinicalTrials.gov/show/NCT01590745	Completed	East Kent Hospitals University NHS Foundation Trust	2017-02-28
NCT04434105	Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04434105	Active, not recruiting	Tanta University	2020-11-30
NCT04391751	Concomitant Basal Joint Arthroplasty and Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT04391751	Active, not recruiting	Hospital Universitari Vall d’Hebron Research Institute	2020-06-30
NCT04354415	Tourniquet vs. No Tourniquet for Carpal Tunnel and Trigger Finger Release	https://ClinicalTrials.gov/show/NCT04354415	Completed	Maisonneuve-Rosemont Hospital	2019-06-20
NCT04347746	Comparison of Interventions in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04347746	Active, not recruiting	Universidade Norte do Paraná	2019-12-12
NCT04346030	Comparison of Ultrasound-guided Corticosteroid Injection Versus Corticosteroid Injection and Hydrodissection for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04346030	Recruiting	Taipei Veterans General Hospital, Taiwan	2021-07-31
NCT04302909	Effectiveness of fESWT in the Treatment of CTS	https://ClinicalTrials.gov/show/NCT04302909	Recruiting	Medical University of Vienna	2021-05-31
NCT04271319	Avazzia HVPC Bio-Electrical Stimulation Technology (BESTâ„¢) Microcurrent CTS RCT	https://ClinicalTrials.gov/show/NCT04271319	Recruiting	Avazzia, Inc	2021-07-31
NCT04268095	Post Operative Dressing After Clean Elective Hand Surgery	https://ClinicalTrials.gov/show/NCT04268095	Recruiting	Tel Aviv Medical Center	2020-12-31
NCT04246216	Percutaneous Electrical Nerve Stimulation for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04246216	Recruiting	Universidad Rey Juan Carlos	2022-12-31
NCT04245098	Carpal Tunnel Syndrome and Amyloidosis	https://ClinicalTrials.gov/show/NCT04245098	Recruiting	Corporacion Parc Tauli	2022-01-08
NCT04235426	Platelet Rich Plasma Injection Versus Surgical and Medical Treatment of Mild-moderate Carpel Tunnel Syndrome.	https://ClinicalTrials.gov/show/NCT04235426	Active, not recruiting	Menoufia University	2021-01-31
NCT04216147	Percutaneous Needle Electrolysis Versus Surgery in the Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04216147	Completed	Universidad de Murcia	2019-01-01
NCT04201652	Comparing Superficial vs. Deep Local Anesthetic Infiltration to Improve Patient Experience During Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT04201652	Recruiting	University of Saskatchewan	2020-08-31
NCT04191538	Conditioning Electrical Stimulation to Improve Outcomes in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04191538	Recruiting	University of Alberta	2022-12-30
NCT04117516	Safety and Efficacy of Percutaneous Carpal Tunnel Release Versus Open Surgery	https://ClinicalTrials.gov/show/NCT04117516	Recruiting	Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana	2021-04-05
NCT04101955	Ultrasound Guided - Incisionless Threaded Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT04101955	Recruiting	Mayo Clinic	2021-09-25
NCT04075357	Amniotic Membrane in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04075357	Completed	Instituto de Oftalmología Fundación Conde de Valenciana	2019-07-21
NCT04072692	Investigation of the Relation Between Trigger Digit and Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04072692	Completed	National Cheng-Kung University Hospital	2019-06-13
NCT04058041	Neural Exercises vs Surgery in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04058041	Recruiting	Universidad Rey Juan Carlos	2020-02-12
NCT04025203	Pain Reduction and Changes in Upper Limb Function Produced by Different Treatments in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04025203	Recruiting	Universidad Europea de Madrid	2019-11-30
NCT04017390	The Effect of Theraworx Foam in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04017390	Recruiting	University of Pittsburgh	2022-01-31
NCT04000932	Platelet Rich Plasma in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04000932	Recruiting	Baskent University	2019-12-30
NCT03996382	Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03996382	Recruiting	Aarhus University Hospital Skejby	2020-11-01
NCT03950401	Prospective Randomized Trial of Monocryl Versus Nylon Suture Closure in Carpal Tunnel Surgery	https://ClinicalTrials.gov/show/NCT03950401	Recruiting	University of California, Davis	2021-08-31
NCT03907956	Efficacy of Dry Needling With the Fascial Winding Technique in the Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03907956	Completed	Universitat Internacional de Catalunya	2020-02-05
NCT03906604	A Comparison of Incisionless Ultrasound Guided Thread Carpal Tunnel Release and Mini Open Carpal in Patients With Bilateral Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03906604	Active, not recruiting	Mayo Clinic	2022-01-31
NCT03880812	Cost Information on Carpal Tunnel Syndrome Treatment Decisions	https://ClinicalTrials.gov/show/NCT03880812	Completed	University of Texas at Austin	2018-12-26
NCT03868449	Question Prompt List for Common Hand Conditions	https://ClinicalTrials.gov/show/NCT03868449	Completed	Stanford University	2019-07-31
NCT03867539	Exparel and Education to Avoid Opioids After Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT03867539	Recruiting	Kettering Health Network	2021-01-31
NCT03863873	Platelet-Rich Plasma in the Treatment of Patients With Idiopathic Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03863873	Completed	Mansoura University	2019-12-01
NCT03810326	Safety and Efficacy of a Device for the Relief of Pain Due to Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03810326	Recruiting	Yuinvent Innovations Ltd.	2020-01-01
NCT03802448	Myofascial Release on Electrophysiological Measures of Pregnant Women With CTS	https://ClinicalTrials.gov/show/NCT03802448	Completed	Cairo University	2013-05-31
NCT03802435	Different Sessions of Perineural Injection With Dextrose for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03802435	Recruiting	Tri-Service General Hospital	2021-07-31
NCT03802422	Vitamin B12 for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03802422	Recruiting	Tri-Service General Hospital	2020-12-31
NCT03795961	Neuromedulatory Effect of Transcranial Direct Current Electrical Stimulation in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03795961	Recruiting	Suez Canal University	2020-01-31
NCT03792945	Comparison of the Efficacy of Corticosteroid Injection and ESWT in Patients With CTS	https://ClinicalTrials.gov/show/NCT03792945	Completed	Ahi Evran University Education and Research Hospital	2019-04-29
NCT03781141	Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery	https://ClinicalTrials.gov/show/NCT03781141	Recruiting	Mayo Clinic	2021-01-01
NCT03747510	PAVmed CarpX Device Clinical Study	https://ClinicalTrials.gov/show/NCT03747510	Completed	PAVmed Inc.	2019-12-30
NCT03742466	Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients	https://ClinicalTrials.gov/show/NCT03742466	Completed	Assiut University	2019-07-30
NCT03730376	Decision Making in Hypothetical Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03730376	Completed	Stanford University	2019-02-01
NCT03729375	The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT03729375	Recruiting	University of South Florida	2020-06-11
NCT03722303	Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03722303	Recruiting	Columbia University	2019-12-31
NCT03675295	Efficacy of Hyalase Hydro-dissection in Treatment of Carpal Tunnel: Randomized Double Blind Controlled Clinical Trial	https://ClinicalTrials.gov/show/NCT03675295	Completed	Assiut University	2018-03-20
NCT03671473	Comparison of Focused and Radial Extracorporeal Shock Wave for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03671473	Recruiting	Tri-Service General Hospital	2020-12-31
NCT03649763	Onset and Duration of Forearm Nerve Blockade	https://ClinicalTrials.gov/show/NCT03649763	Completed	New York School of Regional Anesthesia	2018-12-31
NCT03634618	Efficiency of Mirror Therapy After Carpal Tunnel Surgery	https://ClinicalTrials.gov/show/NCT03634618	Completed	Istanbul University	2017-04-27
NCT03616353	IMpact of Perineural Hydrodissection Over Alternative Therapies in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03616353	Recruiting	Hamilton Health Sciences Corporation	2020-06-30
NCT03598322	The Volume Effect of Hydrodissection for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03598322	Completed	National Taiwan University Hospital	2019-07-01
NCT03582735	Preoperative Neuromobilization Exercises for Individuals With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03582735	Completed	Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal	2018-08-13
NCT03580265	Efficacy of Laser Acupuncture for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03580265	Recruiting	Tri-Service General Hospital	2019-12-31
NCT03576196	Preoperative Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03576196	Completed	Hospital Clínico La Florida	2017-11-30
NCT03548259	Effects of Platelet-rich Plasma in the Surgery of Carpal Tunnel Syndrome: A Randomized Controlled Trial	https://ClinicalTrials.gov/show/NCT03548259	Completed	Cardenal Herrera University	2018-11-05
NCT03532373	Testing of a Tool to Elicit Patient Preferences for CTS	https://ClinicalTrials.gov/show/NCT03532373	Enrolling by invitation	Stanford University	2022-06-30
NCT03498287	Non-invasive CTS Device Clinical Trial	https://ClinicalTrials.gov/show/NCT03498287	Active, not recruiting	Pressure Profile Systems, Inc.	2020-05-31
NCT03495466	Comparison of Local Only Anesthesia Versus Sedation in Patients Undergoing Bilateral Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT03495466	Completed	Ohio State University	2018-12-31
NCT03476486	A Pilot Study to Evaluate the Effectiveness of Ultrasound Guided Looped Thread Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT03476486	Completed	University of Alberta	2018-01-20
NCT03432858	Preoperative Antibiotics for Carpal Tunnel Release Surgery	https://ClinicalTrials.gov/show/NCT03432858	Recruiting	WellSpan Health	2022-12-31
NCT03427983	Hydrodissection as a Treatment for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03427983	Completed	Mayo Clinic	2019-07-31
NCT03411551	Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier’s Block in Patients Undergoing Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT03411551	Completed	Jessa Hospital	2019-12-20
NCT01102868	IMS-treatment and Canalis Carpi Syndrome	https://ClinicalTrials.gov/show/NCT01102868	Completed	NORCE Norwegian Research Centre AS	2012-01-31
NCT01093209	Efficacy of the Interferential Laser Therapy in Pain Reduction in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT01093209	Completed	Hospital Universitario Ramon y Cajal	2010-04-30
NCT01014221	Acupuncture in Patients With Carpal Tunnel Syndrome ~ A Randomized Controlled Trial	https://ClinicalTrials.gov/show/NCT01014221	Completed	Kuang Tien General Hospital	2009-02-28
NCT00991068	Open-Label Study Evaluating Synera® in the Treatment of Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00991068	Completed	ZARS Pharma Inc.	2010-03-31
NCT00988923	Hyperthermia As A Conservative Treatment For Carpal Tunnel Syndrome. A Randomized “Sham” Controlled Trial	https://ClinicalTrials.gov/show/NCT00988923	Completed	Catholic University of the Sacred Heart	2008-09-30
NCT00981565	Mild Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00981565	Completed	North Karelia Central Hospital	2011-09-30
NCT00929123	Mechanisms of Neural Mobilization in the Treatment of Chronic Pain	https://ClinicalTrials.gov/show/NCT00929123	Completed	University of Florida	2008-07-31
NCT00904202	A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions	https://ClinicalTrials.gov/show/NCT00904202	Completed	Endo Pharmaceuticals	2003-06-30
NCT00880295	Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT00880295	Completed	Penn State University	2016-07-26
NCT00845325	Early Motion Following Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT00845325	Completed	University of Missouri-Columbia	2016-04-30
NCT03062722	Efficacy of Keyhole Approach to Carpal Tunnel Syndrome Under Ambulatory Strategy	https://ClinicalTrials.gov/show/NCT03062722	Completed	University of Guadalajara	2015-12-01
NCT00806871	Steroid Injection Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00806871	Completed	Region Skane	2012-04-30
NCT03213847	Superb Microvascular Imaging of Median Nerve in Carpal Tunnel Syndrome: A Novel Technique in Diagnostic Ultrasound	https://ClinicalTrials.gov/show/NCT03213847	Completed	UÅŸak University	2017-11-20
NCT03061149	The Effectiveness of Physical Therapy Modalities in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03061149	Completed	Poznan University of Medical Sciences	2014-02-15
NCT02891512	Very Low Frequency Magnetic Fields Versus the Supplement “Xinepa” in the Treatment of the Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02891512	Completed	University of Roma La Sapienza	2015-08-31
NCT04416867	Radial Extracorporeal Shock Wave Therapy in the Treatment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT04416867	Recruiting	Erzurum Regional Training & Research Hospital	2020-05-30
NCT04043780	Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome	https://ClinicalTrials.gov/show/NCT04043780	Recruiting	Universidad de Zaragoza	2020-03-01
NCT00803257	Effect of Lumbrical Stretching on Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00803257	Completed	University of Pittsburgh	2011-01-31
NCT00678314	Patient Controlled Regional Analgesia Following Carpal Tunnel Release: A Double-Blind Study Using Distal Perineural Catheters	https://ClinicalTrials.gov/show/NCT00678314	Completed	Region Örebro County	2006-01-31
NCT00665132	Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves	https://ClinicalTrials.gov/show/NCT00665132	Completed	Bioness Inc	2008-12-31
NCT00634738	The Treatment of the Median Nerve for the Elimination of the Symptoms Associated With the Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00634738	Completed	Guy Hains Chiropractor	2010-06-30
NCT00634699	The Treatment of Carpal Tunnel Syndrome Using Thumb Pressure Along the Median Nerve	https://ClinicalTrials.gov/show/NCT00634699	Completed	Guy Hains Chiropractor	2010-06-30
NCT00394043	Treatment Efficacy of OMT for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00394043	Completed	University of North Texas Health Science Center	2009-10-31
NCT00336622	Efficacy of Wrist/Hand Splints and Tendon/Nerve Gliding Exercises for Carpal Tunnel Syndrome: A RCT	https://ClinicalTrials.gov/show/NCT00336622	Completed	University of Pittsburgh	2005-03-31
NCT00277563	Short and Long Term Exposure to Unique, Time-Varying Pulsed Electro-Magnetic Fields in Refractory Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00277563	Completed	Weintraub, Michael I., MD, FACP, FAAN	NA
NCT00137735	Gabapentin for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00137735	Completed	Chinese University of Hong Kong	NA
NCT00074893	Protective Brace to Prevent Hand and Arm Injuries	https://ClinicalTrials.gov/show/NCT00074893	Completed	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	NA
NCT00032227	Carpal Tunnel Syndrome: Diagnosis and Treatment Trial	https://ClinicalTrials.gov/show/NCT00032227	Completed	University of Washington	2007-04-30
NCT00029497	Sham Device, Pill Placebo or Treatment For Arm Pain	https://ClinicalTrials.gov/show/NCT00029497	Completed	National Center for Complementary and Integrative Health (NCCIH)	2004-06-30
NCT00435149	Post-operative Mobilization for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00435149	Completed	Vanderbilt University	2011-02-28
NCT00000394	Acupuncture for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT00000394	Completed	George Washington University	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03391336	Median Nerve Injury in US-guided Carpal Tunnel Injections	https://ClinicalTrials.gov/show/NCT03391336	Completed	Tri-Service General Hospital	2017-09-30
NCT03299361	Diffusion Tensor Imaging of the Median Nerve Before and After Carpal Tunnel Corticosteroid Injection in Patients With Carpal Tunnel Syndrome: Feasibility Study	https://ClinicalTrials.gov/show/NCT03299361	Completed	Tri-Service General Hospital	2016-12-31
NCT03166033	Case-control Study on Individual Risk Factors of CTS	https://ClinicalTrials.gov/show/NCT03166033	Completed	Fudan University	2014-12-31
NCT03082027	Pre-operative Sonographic Assessment of The Median Nerve in Carpal Tunnel Syndrome. Does it Affect The Operative Procedure?	https://ClinicalTrials.gov/show/NCT03082027	Completed	Minia University	2016-12-31
NCT03033173	Ratio of the Cross Sectional Area of Median Nerve to Ulnar Nerve in Diagnosing Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03033173	Completed	Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation	2014-12-31
NCT02788734	Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies	https://ClinicalTrials.gov/show/NCT02788734	Completed	University of South Florida	2016-11-19
NCT02672059	Pain In Neuropathy Study	https://ClinicalTrials.gov/show/NCT02672059	Recruiting	King’s College London	2021-06-30
NCT02587897	Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals	https://ClinicalTrials.gov/show/NCT02587897	Active, not recruiting	University of Southern California	2020-07-31
NCT02587728	Carpal Tunnel/Amyloidosis Blood Sample Study	https://ClinicalTrials.gov/show/NCT02587728	Recruiting	University of Miami	2020-11-30
NCT02038205	Ultrasonographic Measurements of the Median Nerve Before and After Splinting for Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02038205	Completed	University of California, Davis	2016-11-30
NCT02276105	Investigation of Psychometric Properties of the EuroQoL EQ-5D-5L in Patients With Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02276105	Completed	Schulthess Klinik	2015-05-31
NCT02261012	Examination of the Pathophysiologic Mechanisms of CRPS by Using QST, CPM, RIC, and Heart Rate Variability QST	https://ClinicalTrials.gov/show/NCT02261012	Completed	Ruhr University of Bochum	2015-04-30
NCT02196220	Ultrasonographic Assessment of Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT02196220	Completed	University of Utah	2019-06-30
NCT01853969	Typing Proficiency Following Carpal Tunnel Release	https://ClinicalTrials.gov/show/NCT01853969	Completed	Vanderbilt University	2015-06-30
NCT01394822	Neuromuscular Ultrasound for Focal Neuropathies	https://ClinicalTrials.gov/show/NCT01394822	Completed	Wake Forest University Health Sciences	2014-03-31
NCT04060875	Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain	https://ClinicalTrials.gov/show/NCT04060875	Enrolling by invitation	Karuna Labs Inc.	2019-08-20
NCT03970408	Median Nerve Excursion During Neurodynamic Mobilization	https://ClinicalTrials.gov/show/NCT03970408	Recruiting	Cairo University	2020-02-01
NCT03909373	Validation of PSFS in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03909373	Recruiting	Stanford University	2020-12-31
NCT03782558	Validation of the Polish Version of the Boston Carpal Tunnel Syndrome Questionnaire	https://ClinicalTrials.gov/show/NCT03782558	Enrolling by invitation	Jagiellonian University	2020-06-30
NCT03779958	Alternatives to Hand Therapy for Hand Surgery Patients	https://ClinicalTrials.gov/show/NCT03779958	Enrolling by invitation	Stanford University	2022-12-31
NCT03499158	Terminal Latency Index, Residual Latency and Median Ulnar F Latency Difference in Carpal Tunnel Syndrome	https://ClinicalTrials.gov/show/NCT03499158	Completed	Ufuk University	2016-03-01
NCT01110759	Medical Review: Hand Surgery After Local Block Versus Non-block	https://ClinicalTrials.gov/show/NCT01110759	Completed	Cedars-Sinai Medical Center	2011-07-31
NCT00987571	Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression	https://ClinicalTrials.gov/show/NCT00987571	Completed	EMG Labs of Arizona Arthritis & Rheumatology Associates	2009-09-30
NCT00856011	Nerve Morphology in Diabetic Patients	https://ClinicalTrials.gov/show/NCT00856011	Completed	Skane University Hospital	NA
NCT02792790	Carpal Tunnel Syndrome and Amyloid Cardiomyopathy	https://ClinicalTrials.gov/show/NCT02792790	Active, not recruiting	The Cleveland Clinic	2021-05-31
NCT04027998	Median Nerve Strain and Applied Pressure Measurement in the Carpal Tunnel Syndrome Patients	https://ClinicalTrials.gov/show/NCT04027998	Recruiting	Tokyo Medical University	2019-07-17
NCT00775333	Nerve Entrapment in Diabetic Patients	https://ClinicalTrials.gov/show/NCT00775333	Completed	Skane University Hospital	NA
NCT00694265	Sonographic Follow-up of Patients With Carpal Tunnel Syndrome Undergoing Surgical or Conservative Treatment	https://ClinicalTrials.gov/show/NCT00694265	Completed	University of Bern	2003-06-30
NCT00357136	Online Survey on Computer Password Usage.	https://ClinicalTrials.gov/show/NCT00357136	Completed	Towson University	2006-12-31
NCT00042419	Work and Health Disparities Among Rural Women	https://ClinicalTrials.gov/show/NCT00042419	Completed	National Institute of Environmental Health Sciences (NIEHS)	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02285868	ATI Evidence-based Guide Investigating Clinical Services	https://ClinicalTrials.gov/show/NCT02285868	Recruiting	ATI Holdings, LLC	2024-01-31
NCT03718598	Carpal Tunnel Syndrome in Pregnant Women	https://ClinicalTrials.gov/show/NCT03718598	Completed	Bezmialem Vakif University	2016-01-01